Tramacet

June 27, 2005 at 4:24 pm | In Prescribing Extra - Drugs | Print Print | 57 Comments

Tramacet has been launched recently and is being heavily promoted in the form of adverts and journal inserts. It contains 325mg of Paracetamol and 37.5mg of Tramadol per tablet.

Given the recent announcement of the withdrawal of Co-proxamol, we feel it would be inappropriate to transfer patients to this drug. We are also concerned that this new product contains subtherapeutic doses of both ingredients.

It currently costs £10.07 for 60 tablets which is over £9 more than the cost of 100 Paracetamol and £3 more than 100 Co-codamol 30/500mg tablets.

Action: There can be no good reason to use Tramacet in any circumstance.

Copyright ©2005 Prescribing Advice for GPs

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  1. i have just been prescribed tramacet. i have been suffering from severe headaches for over a year. am waiting to go for a brain scan. doctor has not said why i keep getting headaches. been taking the tablets for 4 days and my pain is still the same. the pain is in the back of my head and i am losing my hair aswell. am really scared because my moms sister had something similar and they found out she had a brain tumour which later killed her. get dizzy a lot when i stand up. the room starts to spin.

    Comment by v chana — March 31, 2007 #

  2. You should get some more answers from your scan. I’m not surprised you are scared but try not to worry too much until you have more answers.

    Comment by Administrator — April 1, 2007 #

  3. Having had osteoarthritis in one knee since a high impact trauma 10 years ago, I was on co-proxamol for many years to control the pain, which is always there and could flare up to intolerable levels once or twice each year for a month or so.

    When the hounded Dr. Kelly used co-proxamol to commit suicide, causing the short-sighted govmt to recind its licence, I was panicking badly about what possible replacement I might be given. It turned out to be Tramadol.

    I was put on 2 standard 50mg capsules twice daily, and though the pain relief was not as great as via co-proxamol, it was better (and less nauseating) than co-codamol and a hell of a lot cheaper for me than ibuprofen+codeine!

    Anyway the point I wanted to make was that in March this year I fell down some steps and re-traumatised the knee. For the next 3 months until just a week ago, I was in excruciating pain day and night. Tramadol wasn’t very effective, either in 50mg standard caps or 200mg slow release form, so the doctor put me on Tramacet.

    Brilliant! It works for some reason much faster than Tramadol hydrochloride on its own in a gel capsule. Perhaps its the combo of paracetamol? In any case it gives faster, more effective relief than any other form of this drug.

    FYI the slow-release caps are next to useless for severe pain. Although the blood plasma levels are supposed to be maintained at a constant amount, the perceived pain relief is more like a bell curve; no relief for 2 hrs after taking the capsule. Then gradually-increasing relief until it peaks for an hour, before falling off again. One is in horrible pain again well before the next capsule is due.

    Comment by Chris Nixon — June 21, 2007 #

  4. I have been taking 30/500mg of co-codamol (3 a day)for the last 2 years mostly daily, this is to releive the severe pain of whats been diagnosed of I.B.S is this exceptable and is there any danger from continual use.

    Many thanks

    Sean

    Comment by Sean — June 30, 2007 #

  5. Sean,

    If you have these sorts of concerns you really should be speaking to your own doctor.

    There should be no long term problems caused by taking a regular dose of co-codamol 30/500mg of up to 8 tablets per day.

    Co-codamol 30/500mg would not be my first choice as a treatment for IBS but I don’t have access to your medical history and have no idea what else you have tried. As I said above, discuss your concerns with your own doctor and they will be able to advise you.

    Comment by Administrator — June 30, 2007 #

  6. I have been taking tramacet for about 8 months now for a slipped disc in my neck, there is nothing that can be done because the risk is too great for surgery. The Tramacet work very well but the doctor only prescribes 60 at a time, when I start to run out with the week-end approaching I cannot get a repeat prescription, the reason I mention this is due to The Cold Turkey affect, it doesn’t take long for the side affects to start, cannot sleep, sweats, anxious. My doctor has now started to wean me off them, is there any other pain management to be considered.

    Comment by Steve — August 7, 2007 #

  7. Steve,

    There are many strategies you can adopt for pain management that don’t involve pain killing medication. It will depend what is available in your local area but it’s worth talking to your doctor about physiotherapy and accupuncture for example.

    Pain killers may still be required occasionally, or perhaps all the time, but my feeling has always been that the long term aim should be to minimise your use of pain killers so that when your symptoms are really bad you have a fall back position.

    Comment by Matthew Robinson — August 7, 2007 #

  8. I have been taking Tramacet since a fall down the stairs in August 2007. They do relieve the pain and I have tried to wean myself off them by only taking one per day. However I have noticed that I feel nauseos every morning and feel as though I may be addicted to them. The pain is not as bad as when I had the fall but it is still very uncomfortable. I work full time and need the Tramacet to get me through the day. I dont want to take them forever.

    Comment by Julie Matthews — November 24, 2007 #

  9. I had a small surgical procedure done and was given tramacet as an option to use..? Said it was not constipating which was the reason why I tried it. I hate drugs dont take any… I cut them in half and took half a day for two days. The third day I could not sleep, and was in pain so I tried another half… a short time later I started sweating , all my pain was gone, I felt panicky , jumped out of bed…did not know where I was going but knew I was in trouble..? I ended up blanking out on the bathroom floor, I stood up again right away..could not breathe, ears started ringing… I was scared and phoned ambulance… they seemed to think I was going into shock… I will never touch the stuff again.

    Comment by Garry — January 26, 2008 #

  10. I was on Percocet..the Dr. gave me a few samples of Tramacet to try…it’s very new to me and I’m afraid to try it. Do it have the same pain relief as Percocet and would I have any different reactions to it ? I’m not allergic to any opiads that I know of, or acetaminophen. Percocet agreed with me….but now I have none and he gave me these that I’m leary of taking…having lots of pain past few days…I have fibromyalgia.

    Comment by Donna Mercer — March 19, 2008 #

  11. Donna,

    Perocet is similar to Tramacet. It is an opiate style pain killer mixed with paracetamol (acetominophen). If you are okay using Perocet there is no reason to be afraid to try Tramacet.

    The only way you’ll find out how effective it is for you is by trying it. It may work better or it may be less effective. If it is the latter then let your doctor know and he can try something else.

    Comment by Matthew Robinson — March 21, 2008 #

  12. Do British GP’s (NHS) prescribe tramacet? My GP has said he is not allowed to prescribe it.

    Comment by Lisa — April 26, 2008 #

  13. Lisa,

    GPs working for the NHS are allowed to prescribe Tramacet on a national level however there may be other factors such as local guidance, practice policy and clinician preferences for which medication to prescribe.

    If your GP says he is not allowed to prescribe it ask him or her why not and they should be able to justify the decision with their reasoning.

    Comment by Matthew Robinson — April 26, 2008 #

  14. Hi

    Thanks for your response. My GP said that he is not allowed to prescribe combinations. It could be a cost factor so he prescribed masses of paracetamol and Tramadol. I am not particularly happy with this as it appears not to work the same.

    Regard
    Lisa

    Comment by Lisa — April 27, 2008 #

  15. I have just been prescribed Tramacet after suffering a slipped disc in my back, the pain relief is great but I have only been taking them for a couple of days and have started to itch all over and unable to function on them, as a result I have stopped taking them, my pain is severe now and nothing else touches it, what would you suggest?

    Comment by Rachel — July 3, 2008 #

  16. Tramadol is an opiate analgesic and skin itch with opiates is common. A lower dose or an alternative opiate may be worth a try. Consult your doctor for dosing advice or an alternative.

    Comment by Matthew Robinson — July 3, 2008 #

  17. I take tramacet and diclofenac together for the attempted relief of a constant severe headache, only when it is at it’s very worst- when i’m passing out and screaming- do i take meds as otherwise they have no effect.
    Even with this combination (and a pulse dose of amitryptaline every night) i am in ALOT of pain. I’m 16 and have tried lots of levels of codeine, co-codamol, ibuprofen, migraine tablets and other triptans etc. and because of my age neither my Dr. or my previous neuro would prescribe anything stronger.
    When i come down off the tramacet i feel horrible, really really down and irritable, is there anything else i could take that might help the pain?

    Comment by Rach — July 13, 2008 #

  18. Rach,

    Tramadol and codeine are pretty high strength pain killers. There are not many pain killers that are stronger if the correct does is used.

    Without knowing exactly what you’ve tried and in what combination it would be very difficult to make recommendations about what else you could try. It would seem that by trying triptans and amitriptyline that your doctors have suspected migraine but are now trying nerve stabilisers.

    I’d suggest you go back to your doctors and ask what else you can try and what the risks and likely benefits of each option are.

    Comment by Matthew Robinson — July 14, 2008 #

  19. I’ve been on Tramacet for 18 months now, to help combat a permanently trapped nerve that can only be released by surgery – not a path i’m rushing to follow.
    I’ve not noticed any addictive symptoms and can vary the dose from nothing to the maximum of eight per day without any obvious impact.
    That said, when the discomfort / pain is at its maximum, even the full dose only takes the edge off the inherents cramps and aches caused by the trapped nerve, so it’s not going to be long before I join the surgery queue.
    Is there anything else with a little more immediate strength and no addictive impacts that might help me delay the knife?

    Comment by Robert — September 29, 2008 #

  20. Robert,

    Without knowing what you’ve tried in the past and details of your medical history it’s really hard to advise you. There are alternatives and I think you would be best talking over the options with your own doctor. Obviously, surgery is an option you are already aware of, I wonder why you are not taking this option if it offers a cure from your pain.

    Comment by Matthew Robinson — September 29, 2008 #

  21. I have been taking tramacet for a month and a half and stopped and the first night I was tossing and turning all night didn’t think anything of it the next day started alright a bit tired but whatever, later that day I starting feeling like I was getting the flu, then at bedtime was completely restless but at the same time really tired everytime I closed my eyes to sleep something in me freaks out makes me wanna move constantly I was seriously climbing the walls scared me as I had no idea what was happening to me I thought I was going crazy so For some reason I thought of the tramacet and realized I am having withdrawls I hate the way I am feeling anxious uneasy unwell just not me and I have an 8 month old to be taking care of and its hard I don’t want to see anyone or even answer the phone. What can I do to make me me again without pills I never wanna feel like this again, and how long does this last?

    Comment by TJ — October 9, 2008 #

  22. TJ,

    Sounds very much like withdrawal. There is every reason to expect this to pass pretty quickly – within 3 to 4 days.

    You could try weaning yourself off this tablet a bit at a time or put up with these symptoms and get off them quickly.

    You could also contact your doctor for advice if there are other things going on that you haven’t mentioned above.

    Comment by Matthew Robinson — October 10, 2008 #

  23. I’ve had epididymitis and with it really bad pain for quite some while. After 2 rounds of anitbiotics I’ve finally been referred to a urologist. Anyway, I’ve been prescribed Tramacet for pain because I’m allergic to codeine. It works incredibly well for pain management. I’m not sure how it would be for long-term use though (I’ve been taking it about 3 weeks). I’m not sure about withdrawal symptoms either. I’ve taken it in the past for a couple weeks at a time for appendicitis pain (which is excruciating). It was incredible for managing my pain and I really had no withdrawal symptoms other than maybe a day of mild diarrhea.

    I would recommend if anyone is going through withdrawal they should talk to their doctor. Perhaps there are ways to manage the symptoms other than weaning yourself off of the drug.

    Also to anyone experiencing itching when first taking it Benadryl might help (I’d check with a Doctor first though). And the itching doea go away after a few days of use. Also with itching perhaps your taking too much at first. You could start out with 1 tablet of tramacet or 1 tramacet and 1 Tylenol.

    Comment by AZM — December 31, 2008 #

  24. I have been taking Tramacet since co-proxamol was stopped. I am trying to stop taking them, but the withdrawls make me feel lousy, I am a 60 year old women and not in bad nick for my age excpet for my arthritis. However, I have no sense of smell. Is this a side effect of Tramacet? I am having acupuncture to try to restore it as an MRI scan showed only slight damage to my olfactory nerve after an operation to remove nasal polyps.

    Comment by jean robinson — January 13, 2009 #

  25. Jean,

    Altered sense of smell is not a listed side effect in the product information but it has been reported to UK regulatory authorities on three occasions.

    Comment by Matthew Robinson — January 13, 2009 #

  26. i take oxycontin and oxynorm and have some tramacet as well, I have had for the last couple of days the most excruciating chest pain but I think it might be an ulcer is this related to the tramacet at all

    Comment by georgina — January 26, 2009 #

  27. Georgina,

    Tramacet is a combination of paracetmaol and tramadol. Neither ingredient is known for causing ulcers but tramadol is an opioid analgesic and these can sometimes cause palpitations and changes in heart rate. You should see your doctor for a check.

    Comment by Matthew Robinson — January 27, 2009 #

  28. have been taking tramacet for about a year now due to sore back and legs,me and my wife are going to start trying for a baby,will the tramacet affect me in any way ??

    Comment by steven owen — March 5, 2009 #

  29. Steven,

    There are no known problems in men listing in the product literature but if you have any concerns you should discuss them with your own doctor.

    Comment by Matthew Robinson — March 6, 2009 #

  30. Hello
    I was given tramacet last year for my Rheumatoid arthritis pain but i only took the first dose as i was vomiting sweating and dizzy within an hour of taking them i then fell asleep and still felt ill into the afernoon of the next day i work full time and drive so there was no way i could function like that. I now have co codamol 15/500 but they make me feel ill too mostly nauseous and sweaty but also sometimes they make me vomit – i have been avoiding taking them but am struggling also i am unable to take any ibuprofen or related meds is there anything else i can discuss with my GP as they seem to be at a loss what else i can have now? i also have plaquenil and cleloxib.

    Comment by Angela — March 13, 2009 #

  31. Angela,

    There is a possibility that your symptoms are being caused by the opiate component of the co-codamol (codeine). These effects are usually dose related so a dose reduction may help you. There is a co-codamol 8/500 tablet that might be worth trying.

    Comment by Matthew Robinson — March 13, 2009 #

  32. Tramacet has been a godsend to me. After not finding relief from the meds my first doctor prescribed, I sought a second opinion from a military doctor for relief from nerve pain of prolapsed discs due to an accident and I was prescribed Tramacet and Arthrotec 75. What a wonderful difference they made. I eventually needed surgery and that made a big improvement in my symptoms, though I have still had some pain from time to time (generally when I have overdone it or moved in a way I shouldn’t) and need pain medication for a limited time, and the only thing that has helped is Tramacet taken together with Arthrotec. The neurosurgeon who did the surgery was concerned about addictive properties and wanted me to take Lyrica instead, but since weight gain is common with Lyrica and weight gain aggravates my symptoms I have not used that but instead have stayed with Tramacet. Over the three years I have used it for both long and short periods, I’ve never noticed any withdrawal symptoms, and can stop it easily and suddenly when I no longer need pain relief without headaches, nausea or any other symptoms. My chief complaint about Tramacet is that it takes about an hour and a half to two hours to work, and then the relief only seems to last about four hours max, about two hours short of when I could take another one according to dosage. It does make me itch a bit, but not excessively and I don’t find that unpleasant at all. During its peak effectiveness it is very relaxing and is the first medication that I’ve taken that actually takes away all of the pain, and while it does make me drowsy if I don’t want to sleep or have work to do, I could still function fine, of course except driving. However, if I wanted to sleep, it would take me into a lovely, restful sleep. I’m also pleased with the protective action Arthrotec offers my stomach since I had gastritis off and on over the years, and these medications do not provoke it.

    Comment by Sara — March 15, 2009 #

  33. What is the risk of taking amitriptyline 20mg at night and half of a tramacet at night. I’m afraid of taking them together even though both would be a low dose because of there interaction. I have severe pain all day long on my left side due to nerve pain ( trapped nerve in my shoulder) also jaw face pain, osteoporosis joint and muscle pain and inflammation. Sleeping is difficult. I just want to have a restful sleep and wake up with out pain. Tramacet is effective but I take it in small doses. No more then two in a day. i’m also on Lyrica 300mg a day. I do the relaxation meditation, excercise vitamin b’s any other supplements as well as any other natural theraphy that your suppose to do. Chiro etc. I have neck braces and wear a mouth gaurd for TMJ Waiting on a rheumatologist.

    Thanks

    Comment by jay-Anne — March 28, 2009 #

  34. Jay-Anne,

    Taking tramadol and amitriptyline together will increase the risks of sedation. Both of these drugs can also increase the liklihood of seizures. However, you apprear to be taking them both at low doses so the risks will be minimised. If you are concerned speak to your own doctor first as they will have full details of your medical history and can therefore advise you better.

    Comment by Matthew Robinson — March 30, 2009 #

  35. For my small fibre neuropathy in my feet I’ve been on Lyrica, Neurontin, Amitripteline, Tegratol, Tramadol and Tramacet. I walk with a cane to relieve the pressure on my feet. Tramacet is a Godsend. It is the only drug that diminishes the pain, and the only drug that had zero side-effects (on me). I take it “as needed”, usually once a week or whenever I know I have to walk (IE a grocery store) with absolutely no withdrawal symptoms. Withdrawal from the other drugs (except Amitripteline) was pure, concentrated torture. Just thinking about it brings tears to my eyes. Tramacet is the main reason I am still able to work. I could not disagree more with your “action” statement. If there is something better on the market, what reasons would my 3 neurologists have for not prescribing it?

    Comment by Martini — April 20, 2009 #

  36. Martini,

    It is strange that you have had such problems with tramadol yet none with tramacet. Tramacet is simply a combination of paracetamol and tramadol with a premium price attached, hence my advice.

    Comment by Matthew Robinson — April 21, 2009 #

  37. After checking for a few days for a reply, today I noticed that my comment has been deleted. I wonder why an administrator would do that?

    As I stated earlier, I’ve been on Tramacet for my small fibre neuropathy in my feet. I walk with a cane. Tramacet has been an absolute Godsend. I’ve been on Lyrica, Ametripteline, Tegratol and Tramadol with no luck.

    Tramacet is the ONLY one that has given me relief in my feet and kept me working, which doesn’t make much sense considering the pure Tramadol barely took the edge off. All of the others, except Ametripteline, have caused severe withdrawal symptoms and side effects. With Tramacet I can take 2 a day or 2 a week with zero withdrawal symptoms. Just thinking about the withdrawal from the Lyrica & Tramadol brings tears to my eyes.

    Tramacet is somehow is the only one that reduces my pain. Other than my small fibre neuropathy, I am perfectly healthy. So if there is a better drug on the market, why would my three different neurologists not suggest it?

    Comment by Martin — April 23, 2009 #

  38. Martin,

    There is nothing sinister going on in the background. Sadly my hosting company have had an outage this week and thanks to your comment I’ve realised that I have some data loss. Two articles has disappeared as well as you comment and my reply.

    I have some database backups available that contain this information so I’ll work to restore them to the site. Thanks for highlighting the issue.

    Comment by Matthew Robinson — April 24, 2009 #

  39. Glad I somehow helped! Sorry for implying anything unsavoury.

    I also cannot explain why Tramadol isn’t working other than (I was told) it is a slow-release all-day type. I suppose it is released a little TOO slowly.

    Comment by Martin — April 29, 2009 #

  40. Martin,

    Tramadol is available in a modified release form but should also be available in an immediate release capsule containing 50mg of tramadol. This may suit you better but if you are currently stable on Tramacet® then it may be unwise to change.

    Comment by Matthew Robinson — April 30, 2009 #

  41. Have cervical spondylosis and optic neuritis and neurotic affection angi odeamo urtic aria.(excuse spelling).
    Was on Tramacet, great solution after years of cocodamol, I could sleep at nights. dr took me off it because of government guidelines, he told me it was because the drug is sooo addictive. He put me on codiene phosphate and paracetamol. I rarely take the parcetamol it is not very effective, tramacet gave me no stomach problems, I think the codeine phosphate gives me stomach cramps and diahorrea. Could I use anything else for pain relief.

    Comment by b morris — July 5, 2009 #

  42. B Morris,

    Tramacet is simply a mixture of tramadol and paracetamol. Both are at lower than normal doses and the product is expensive when compared to the alternatives. I’d suggest you return to your doctor and discuss the alternatives having tried paracetamol and codeine unsuccessfully. Perhaps tramadol as a single agent might be useful for you.

    Comment by Matthew Robinson — July 6, 2009 #

  43. thank u

    Comment by b morris — July 7, 2009 #

  44. Just had tramacet and baclofen after admitting to my GP that on Monday night I needed alcohol to relax my muscle spasm. I have been on 30/500 co-codamol for 4 years and diazepam, while I have no feeling of addiction, I am needing a larger dosage to get relief.
    So far, 24 hours, I feel much better and had no need or desire for diazapem or co-co, and slept for 7 hours without waking. I didn’t take the sleeping pill she gave me. My GP is fab as she does listen and is willing to try anything to help. I’ve been referred to a pain mgt centre for help. I think the last resort of alcohol was the last straw for her though and she told me a brandy before bedtime is OK, but the equivalent of 10 pub measures of wodka is not OK. I agree as I am a non drinker usually but this was a desperate last resort.

    But so far so good for tramacet and baclofen.

    Comment by Susan — August 12, 2009 #

  45. My GP changed me over from Tramadol to Tramacet a couple of weeks ago. Iv’e found that the Tramacet aren’t as effective in relieving the pain than the Tramadol was. I have asked for a repeat prescription today and have asked to go back onto the Tramadol. The problem is Spondylitis from the top of my neck and down my back. The pain i’m suffering is mainly down the side of my head and across my left shoulder, it is excrutiating. It’s leaving me feeling very debilitated and depressed, I seem to be getting very little relief from it. My GP has ordered another x-ray of the back of my neck to check for any further deterioration and has advised that on the result of this x-ray he may be able to prescribe pain patches or injections. I have also in the last couple of weeks, been seeing an osteopath, this has helped slightly. If anyone has any further suggestions I would be very grateful to hear them.

    Comment by Carol Corrigan — August 18, 2009 #

  46. Can I take Tremadol and benadryl at the same time? Tremadol for the pain and benadryl for the itching

    Comment by judith — January 9, 2010 #

  47. @Judith,

    Benadryl is a brand name for a range of products so without knowing exactly which product (and therefore that active ingredients) it’s difficult to say for sure. You are probably going to be slightly more drowsy but other than that it should be safe. It is best to check with your local pharmacist to be entirely sure though.

    Comment by Matthew Robinson — January 9, 2010 #

  48. Hi, I suffer with SLE (Lupus) I’ve suffererd with it for years but had years of doctors telling me it was lack of muscle mass, lack of exercise, torn ligaments etc, the list goes on, until I had blood tests and saw a specialist (I’m 22 now and remember my first pains when I was 14).. I was only diagnosed in November last year. I’m currently on Celoxib and Plaquenil neither of which seem to be helping at all, I’m currently having a massive flare up and I’m in agony with my knees and shoulders, my doctor has finally prescribed me co-codamol but of the lowest dose 8/500, 2 tablets 4 times daily, this isn’t helping either, my mums partner suffers with ME and takes Tramadol 30/500 and gave me a couple of these to try, just to see if it can take the edge off but I’m very wary of it, I really don’t want to take anything the doc hasn’t prescribed but I’m in so much pain I don’t think they understand. Am I right in thinking you can’t take co-codamol and Tramadol at the same time? And if I’m right how long after taking tramadol should you leave before taking co-codamol again? I can’t wait to see my Rheumatologist again on the 5th March, I really need something to take away the pain or at least numb it a bit, steroid injection seemed to be the only thing that worked but that was only brief, it wore off after 4 weeks :-( ..

    Comment by Christine — February 14, 2010 #

  49. @Christine,

    I can sympathise with your predicament. You have obviously tried several medicines, none of which seem to be providing you any relief.

    It’s a difficult situation to suggest you take someone else’s medication – this is never a good solution to a problem. Would it be possible for you to contact your local out of hours service – they may be able to arrange a supply of stronger pain killers for you before your doctor is available on Monday?

    Comment by Matthew Robinson — February 14, 2010 #

  50. I have fibromyalgia, have been on codeine but doctor has now put me on tramacet, am worried about taking first dose as I seem to get bad reactions to the various meds I have tried. What is your opinion on prescribing tramacet for fibromyalgia? (also have IBS, dysthymia, and mild arthritis). I use mebeverine/lactulose for IBS, cetraben for dry skin, carbomer for dry eyes. How safe is tramacet for long term use? Any info appreciated.

    Comment by julie — June 17, 2010 #

  51. @Julie,

    I can only presume your medication has been changed because the codeine was not really helping. Tramacet is more expensive than the alternatives but if all of the alternatives have been tired already it may be a last resort option. If you still have concerns you should raise these with your doctor.

    Comment by Matthew Robinson — June 17, 2010 #

  52. Just a word of warning to tramacet users,, i was prescribed tramacet 2 years ago for broken ribs, they worked a treat and kept pain to a minimum, I knew if i had missed my tablet as the pain came with a vengance. Once the ribs healed i thought the time was right to ween off the tabs,, I found this so hard to come off the tabs, if i missed a doze i could not sleep at night, i tossed and turned kicked and twitched all night and kept my wife from getting a good nights sleep,, so i took one Tramacet on a daily basis at 6 oclock and this ensured a normal lifestyle and a normal night sleep.
    I am now in the process of reducing from one a day to half then miss a half and eventualy get off them completely but believe me it is very hard.
    I have been on holiday all week and my main objective has been to get off the Tramacet once and for all.
    I guess what i am trying to warn everyone is that Tramacet is addictive and a killer to get off if used for a long period of time so follow the guidelines and information from doc and please dont get hooked on them like me,,, wish me luck

    Comment by Alan — July 17, 2010 #

  53. UPDATE,,,, managed to get off the Tramacet,, three nights with very little sleep though,, cold turkey!!! Twitched for Scotland and had to get out of bed to allow the wife to get some kip.
    Now that the pain killer is out my system the pain is back lol,, so at least i know they were good, however, now i know i need to return to the doc as the problem is still there. no more addictive drugs for me though……

    Comment by Alan — July 21, 2010 #

  54. I have severe spinal damage, fibromyalgia, IBS to name but a few. After the pain clinic have tried every painkiller going my doctor suggested I try the combination of Paracetamol and tramadol. EXCELLENT, I have long term pain, and chose only to use pain meds when I am in flare up. HOWEVER, I have had a gastric bypass (R.en.Y)As I now have a pouch and not a full stomach the affect of taking this combination caused terrible nausea and dizzyness, without sounding dramatic I felt I was dying. The only alternative I was offered was morphine patches which having used before do not want to go back on as they caused no end of problems with side affects. With the help of the pharisutical department in my hospital I have just been given Tramacet in the hope it will work the same without the side affects my bypass cause. Have you any knowledge of its reaction in bypass patients as I am sat here terrified to take it, but in so much pain.Sorry my message is so long. Judy

    Comment by Judy Parry — July 30, 2010 #

  55. I omitted to add that I have chronic arthritus and a cracked and eroded hip………… I am only 57

    Comment by Judy Parry — July 30, 2010 #

  56. @Judy,

    I have no personal experience of using Tramacet at all, much less in patients how have had gastric bypass surgery. It is a lower dose of tramadol in these tablets than in the tramadol capsules (at least it is here in the UK). If you pain is that bad surely it’s worth chancing the side effects so at least you know if the new tablets suit and get some relief or you know you need an alternative.

    Comment by Matthew Robinson — July 31, 2010 #

  57. I started taking a combo of Tramacet and Tramadol and Ibuprofen for quite severe chronic pain. Coinciding with this I started gaining weight although with the pain control my mobility has increased so this doesnt make sense. Does anyone know if it is possible that one of these drugs causes weight gain? Thanks

    Comment by Kate Argyle — August 22, 2010 #

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