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Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Tramacet

Tramacet has been launched recently and is being heavily promoted in the form of adverts and journal inserts. It contains 325mg of Paracetamol and 37.5mg of Tramadol per tablet.

Given the recent announcement of the withdrawal of Co-proxamol, we feel it would be inappropriate to transfer patients to this drug. We are also concerned that this new product contains subtherapeutic doses of both ingredients.

It currently costs £10.07 for 60 tablets which is over £9 more than the cost of 100 Paracetamol and £3 more than 100 Co-codamol 30/500mg tablets.

Action: There can be no good reason to use Tramacet in any circumstance.

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108 Comments to “Tramacet”

  1. Can I take Tremadol and benadryl at the same time? Tremadol for the pain and benadryl for the itching

    Comment by judith — January 9, 2010 #
    Reply

    1. @Judith,

      Benadryl is a brand name for a range of products so without knowing exactly which product (and therefore that active ingredients) it's difficult to say for sure. You are probably going to be slightly more drowsy but other than that it should be safe. It is best to check with your local pharmacist to be entirely sure though.

      Comment by Matthew Robinson — January 9, 2010 #
      Reply

  2. My GP changed me over from Tramadol to Tramacet a couple of weeks ago. Iv'e found that the Tramacet aren't as effective in relieving the pain than the Tramadol was. I have asked for a repeat prescription today and have asked to go back onto the Tramadol. The problem is Spondylitis from the top of my neck and down my back. The pain i'm suffering is mainly down the side of my head and across my left shoulder, it is excrutiating. It's leaving me feeling very debilitated and depressed, I seem to be getting very little relief from it. My GP has ordered another x-ray of the back of my neck to check for any further deterioration and has advised that on the result of this x-ray he may be able to prescribe pain patches or injections. I have also in the last couple of weeks, been seeing an osteopath, this has helped slightly. If anyone has any further suggestions I would be very grateful to hear them.

    Comment by Carol Corrigan — August 18, 2009 #
    Reply

  3. Just had tramacet and baclofen after admitting to my GP that on Monday night I needed alcohol to relax my muscle spasm. I have been on 30/500 co-codamol for 4 years and diazepam, while I have no feeling of addiction, I am needing a larger dosage to get relief.
    So far, 24 hours, I feel much better and had no need or desire for diazapem or co-co, and slept for 7 hours without waking. I didn't take the sleeping pill she gave me. My GP is fab as she does listen and is willing to try anything to help. I've been referred to a pain mgt centre for help. I think the last resort of alcohol was the last straw for her though and she told me a brandy before bedtime is OK, but the equivalent of 10 pub measures of wodka is not OK. I agree as I am a non drinker usually but this was a desperate last resort.

    But so far so good for tramacet and baclofen.

    Comment by Susan — August 12, 2009 #
    Reply

  4. thank u

    Comment by b morris — July 7, 2009 #
    Reply

  5. Have cervical spondylosis and optic neuritis and neurotic affection angi odeamo urtic aria.(excuse spelling).
    Was on Tramacet, great solution after years of cocodamol, I could sleep at nights. dr took me off it because of government guidelines, he told me it was because the drug is sooo addictive. He put me on codiene phosphate and paracetamol. I rarely take the parcetamol it is not very effective, tramacet gave me no stomach problems, I think the codeine phosphate gives me stomach cramps and diahorrea. Could I use anything else for pain relief.

    Comment by b morris — July 5, 2009 #
    Reply

    1. B Morris,

      Tramacet is simply a mixture of tramadol and paracetamol. Both are at lower than normal doses and the product is expensive when compared to the alternatives. I'd suggest you return to your doctor and discuss the alternatives having tried paracetamol and codeine unsuccessfully. Perhaps tramadol as a single agent might be useful for you.

      Comment by Matthew Robinson — July 6, 2009 #
      Reply

  6. Glad I somehow helped! Sorry for implying anything unsavoury.

    I also cannot explain why Tramadol isn't working other than (I was told) it is a slow-release all-day type. I suppose it is released a little TOO slowly.

    Comment by Martin — April 29, 2009 #
    Reply

    1. Martin,

      Tramadol is available in a modified release form but should also be available in an immediate release capsule containing 50mg of tramadol. This may suit you better but if you are currently stable on Tramacet® then it may be unwise to change.

      Comment by Matthew Robinson — April 30, 2009 #
      Reply

  7. Martin,

    There is nothing sinister going on in the background. Sadly my hosting company have had an outage this week and thanks to your comment I've realised that I have some data loss. Two articles has disappeared as well as you comment and my reply.

    I have some database backups available that contain this information so I'll work to restore them to the site. Thanks for highlighting the issue.

    Comment by Matthew Robinson — April 24, 2009 #
    Reply

  8. After checking for a few days for a reply, today I noticed that my comment has been deleted. I wonder why an administrator would do that?

    As I stated earlier, I've been on Tramacet for my small fibre neuropathy in my feet. I walk with a cane. Tramacet has been an absolute Godsend. I've been on Lyrica, Ametripteline, Tegratol and Tramadol with no luck.

    Tramacet is the ONLY one that has given me relief in my feet and kept me working, which doesn't make much sense considering the pure Tramadol barely took the edge off. All of the others, except Ametripteline, have caused severe withdrawal symptoms and side effects. With Tramacet I can take 2 a day or 2 a week with zero withdrawal symptoms. Just thinking about the withdrawal from the Lyrica & Tramadol brings tears to my eyes.

    Tramacet is somehow is the only one that reduces my pain. Other than my small fibre neuropathy, I am perfectly healthy. So if there is a better drug on the market, why would my three different neurologists not suggest it?

    Comment by Martin — April 23, 2009 #
    Reply

  9. Martini,

    It is strange that you have had such problems with tramadol yet none with tramacet. Tramacet is simply a combination of paracetamol and tramadol with a premium price attached, hence my advice.

    Comment by Matthew Robinson — April 21, 2009 #
    Reply

  10. For my small fibre neuropathy in my feet I've been on Lyrica, Neurontin, Amitripteline, Tegratol, Tramadol and Tramacet. I walk with a cane to relieve the pressure on my feet. Tramacet is a Godsend. It is the only drug that diminishes the pain, and the only drug that had zero side-effects (on me). I take it "as needed", usually once a week or whenever I know I have to walk (IE a grocery store) with absolutely no withdrawal symptoms. Withdrawal from the other drugs (except Amitripteline) was pure, concentrated torture. Just thinking about it brings tears to my eyes. Tramacet is the main reason I am still able to work. I could not disagree more with your "action" statement. If there is something better on the market, what reasons would my 3 neurologists have for not prescribing it?

    Comment by Martini — April 20, 2009 #
    Reply

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