- Prescribing Advice for GPs - https://www.prescriber.org.uk -

Ethosuximide capsules discontinued

The antiepileptic Ethosuximide, in capsule form, is being discontinued with immediate effect. The product is available as Zarontin and Emeside. Zarontin Liquid will remain available.

There have been long running stock problems with Zarontin that have rapidly depleted stock of Emeside and it now appears that the manufacturers of both products have decided to abandon further attempts to meet market demand with a product that often fails to meet the expected quality standards.

Action: Patients who are prescribed Ethosuximide in capsule form should be identified and referred for specialist advice. The liquid preparation remains available but may not be suitable for some patients.