Doxepin (Sinequan)® capsules are being discontinued in all strengths according to the National Electronic Library for Medicines.
Doxepin is a tricyclic antidepressant with sedative properties. It is expected that supplies will be exhausted by October 2006 although some strengths may disappear sooner.
Doxepin is not widely used but is not available generically and therefore alternative products will need to be used if treatment needs to continue. Amitryptiline, Dosulepin or Clomipramine may be suitable choices.
Action: Clinicians should be aware of this products discontinuation and may wish to identify individuals currently taking this drug. Alternative treatments will need to be investigated if treatment will continue beyond October 2006.
Update: In early 2022 several generic manufacturers are continuing to supply doxepin in the UK. It appears to be readily available in 25mg and 50mg strengths.
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