In a press statement it is claimed that orlistat is associated with a significant increase in aberrant crypt foci, which are widely believed to be a precursor to colon cancer. This comes at a time when orlistat is being considered for availability to purchase "over the counter" in community pharmacy.
Action: Clinicians who prescribe orlistat should be aware of this development. Patients may ask questions if this information is reported in the media.
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