Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

FDA petitioned to ban Orlistat

Public Citizen have petitioned the Food and Drugs Administration in the United States to withdraw Orlistat (Xenical)® from the market amid claims it may be linked to colonic cancer.

In a press statement it is claimed that orlistat is associated with a significant increase in aberrant crypt foci, which are widely believed to be a precursor to colon cancer. This comes at a time when orlistat is being considered for availability to purchase "over the counter" in community pharmacy.

Action: Clinicians who prescribe orlistat should be aware of this development. Patients may ask questions if this information is reported in the media.

[Source: PharmaGossip]

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