- Prescribing Advice for GPs - https://www.prescriber.org.uk -

FDA petitioned to ban Orlistat

Public Citizen have petitioned the Food and Drugs Administration in the United States to withdraw Orlistat (Xenical)® from the market amid claims it may be linked to colonic cancer.

In a press statement it is claimed that orlistat is associated with a significant increase in aberrant crypt foci, which are widely believed to be a precursor to colon cancer. This comes at a time when orlistat is being considered for availability to purchase "over the counter" in community pharmacy.

Action: Clinicians who prescribe orlistat should be aware of this development. Patients may ask questions if this information is reported in the media.

[Source: PharmaGossip]