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Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

MeReC Extra 23

The National Prescribing Centre has published MeReC Extra 23, it details the results of the CATIE Study, changes to non-medical prescribing and how to avoid information overload.

The CATIE Study was a randomised controlled study of antipsychotic medication set up to examine the time-to-discontinuation over an 18-month period. Approximately 75% of the participants discontinued their medication at some point in the study due to side effects, lack of efficacy or for some other reason. MeReC concludes that there is no ideal antipsychotic for all patients and that treatment choice should be based upon the trade off between efficacy and side effects.

The rest of this MeReC details the changes in legislation affecting nurse and pharmacist prescribing and clarifies the differences in practical terms between independent and supplementary prescribing. The final section contains pointers to valuable sources of evidence-based information such as NICE, The Cochrane Library and Clinical Evidence.

Action: Clinicians who treat mental illness will find the review of the CATIE study of interest. This MeReC will also be useful to non-medical prescribers and their employers.

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