- Prescribing Advice for GPs - https://www.prescriber.org.uk -

Varenicline safety update

The Medicines and Healthcare products Regulatory Agency has announced an update to the product information for varenicline (Champix®) highlighting concerns over suicidal thoughts and behaviour.

Following a European review in conjunction with the European Medicines Agency (EMEA) it has been recommended that:

Action: Clinicians should avoid using varenicline in patients with underlying mental illness. Patients who are prescribed varenicline should be advised as recommended above.