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Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Drug Safety Update, Issue 8

The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update Issue 8 (PDF).

This issue includes the following drug safety advice articles:

  • Ketoconazole: restricted indications
  • Telbivudine: risk of peripheral neuropathy with pegylated interferon
  • Modafinil: serious skin reactions, hypersensitivity, and psychiatric symptoms

In addition, this issue contains hot topic information about sales restrictions for nasal decongestants containing pseudoephedrine or ephedrine because of concerns about diversion into the illegal manufacture of methylamphetamine and informs readers of the new and improved electronic Yellow Card for the reporting of suspected adverse drug reactions.

Action: Clinicians will find this publication to be a useful review of current issues in drug safety.

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