Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Review of treatments for SUI

The Annals of Internal Medicine has published the results of a systematic review of randomised controlled trials of non-surgical treatments for stress urinary incontinence (SUI).

The review identified 97 trials and 3 existing systematic reviews. The review found that pelvic floor exercises with or without bladder training resolved or improved urinary incontinence compared with regular care. Oral hormone therapy made urinary incontinence worse while transdermal and vaginal oestrogen produced inconsistent improvements. Oxybutynin or tolterodine resolved urinary incontinence compared with placebo but adrenergic drugs had no effect and duloxetine improved symptoms without resolution.

Action: The results of study are consistent with the existing NICE Guidance. Clinicians should continue to implement these recommendations.

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