- Prescribing Advice for GPs - https://www.prescriber.org.uk -

Coversyl and Coversyl Plus discontinued

Coversyl® and Coversyl Plus® are being discontinued and replaced by Coversyl Arginine® and Coversyl Arginine Plus® according to the manufacturer.

This decision has been taken to allow for "the global simplification and harmonisation of the manufacturing process for perindopril". The new products also benefit from a longer shelf life. This discontinuation only applies to the branded products and should not impact upon generic perindopril. Patients prescribed branded perindopril or the combination product will need to have their treatment reviewed and amended.

A phased change over period is expected due to the overlap of both products in the supply chain; the new product will be distributed from 1st April 2008 with supplies of the existing product expected to last for about 8 weeks. The licensed indications for the new products are identical to those being discontinued.

Coversyl Arginine is not dose equivalent to the existing perindopril products; conversion details are as follows:

Action: Clinicians should be aware of this discontinuation. Patients who are currently prescribed branded Coversyl or Coversyl Plus will need to be reviewed and have their prescriptions altered.