Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

MTRAC sitagliptin review updated

The Midlands Therapeutic Review and Advisory Committee has published an updated review of sitagliptin (Januvia®).

This review places sitagliptin as having a lower place in therapy but supported by stronger evidence. In combination with other hypoglycaemic drugs it has been shown to lower HbA1c to a greater extent than placebo and has been shown to be non-inferior to glipizide.

MTRAC recommends that, "sitagliptin is suitable for prescribing in primary care upon the advice of a specialist or a GP with a special interest in diabetes". This update notes that sitagliptin can now be used, within license, in combination with metformin and a sulphonylurea for patients who fail to achieve adequate glycaemic control.

Action: Clinicians should be aware of the licence extension for sitagliptin. This drug is still new to the market and should be used cautiously; any suspected adverse drug reactions should be reported through the YellowCard system.

Share 'MTRAC sitagliptin review updated' on Email Share 'MTRAC sitagliptin review updated' on Delicious Share 'MTRAC sitagliptin review updated' on Digg Share 'MTRAC sitagliptin review updated' on Facebook Share 'MTRAC sitagliptin review updated' on Google+ Share 'MTRAC sitagliptin review updated' on reddit Share 'MTRAC sitagliptin review updated' on StumbleUpon Share 'MTRAC sitagliptin review updated' on Twitter

atomic-wealth

One Comments to “MTRAC sitagliptin review updated”

  1. [...] places sitagliptin as having a lower place in therapy but supported by stronger evidence. It was previously known that in combination with other hypoglycaemic drugs it has been shown to lower HbA1c to a greater [...]

    Pingback by Prescribing Advice For GPs » MTRAC Sitagliptin Review Updated — April 23, 2010 #
    Reply

Leave a Comment

(required)

(required)


Prescribing Advice for GPs is powered by WordPress.
Subscribe for Free to our RSS or Atom Feeds for New Entries.
Akismet has protected Prescribing Advice for GPs from 789,427 spam comments.

atomic-wealth
fond-illness
summer