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Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Drug Safety Update, Issue 11

The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update Issue 11 (PDF).

This issue includes the following drug safety advice articles:

  • Natalizumab (Tysabri): safety overview—progressive multifocal leukoencephalopathy, hypersensitivity, and hepatotoxicity
  • Nicorandil: gastrointestinal ulceration

In addition, this issue contains a hot topic containing information about
recent data from the ENHANCE trial and also a stop press warning that several herbal products available for erectile dysfunction have been found to contain prescription only drugs including oral hypoglycaemic agents.

Action: Clinicians will find this publication to be a useful review of current issues in drug safety.

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