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Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Drug Safety Update - March 2009

The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for March 2009 (PDF).

This issue contains a hot topic about the public perception of herbal medicines, a yellow card update that focusses on the rare adverse drug reaction of progressive multifocal leukoencephalopathy (PML) and drug safety updates in the following areas:

  • Methylphenidate: updated guidance on safe and effective use in ADHD
  • Atomoxetine: risk of psychotic or manic symptoms
  • Antipsychotics: use in elderly patients with dementia
  • Exenatide (Byetta): risk of severe pancreatitis and renal failure
  • Bisphosphonates: atypical stress fractures

Action: Clinicians will find this publication to be a useful review of current issues in drug safety.

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One Comment to “Drug Safety Update - March 2009”

  1. [...] and diaphyseal femur fractures). The Medicines and Healthcare products Regulatory Agency reviewed the risk of atypical stress fractures with alendronate in the March 2009 issue of Drug Safety [...]

    Pingback by Prescribing Advice for GPs » Bisphosphonates and fracture risk — October 19, 2010 #

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