☀️     🌓

Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Drug Safety Update - May 2010

The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for May 2010 (PDF).

This issue contains drug safety advice in the following areas:

  • Possibility of an increased risk of persistent pulmonary hypertension in the newborn of mothers receiving selective serotonin reuptake inhibitors (SSRIs) and selective noradrenaline reuptake inhibitors (SNRIs) in pregnancy
  • Increased risk of bone fractures in patients receiving SSRIs and tricyclic antidepressants (TCAs)
  • An interaction between carbapenem antibiotics and valproic acid that results in decreased blood levels of valproic acid
  • Reminder to prescribe oral tacrolimus by brand name to avoid medication errors as a result of brand swapping since the brand are not interchangeable
  • Warning about the increased risk of myopathy in patients receiving the highest licensed dose of simvastatin (80mg)

Action: Clinicians will find this publication to be a useful review of current issues in drug safety.

Share 'Drug Safety Update - May 2010' by emailShare 'Drug Safety Update - May 2010' on FacebookShare 'Drug Safety Update - May 2010' on TwitterShare 'Drug Safety Update - May 2010' on LinkedInShare 'Drug Safety Update - May 2010' on reddit


No Comments to “Drug Safety Update - May 2010”

Leave a Comment

Your email address will not be published. Required fields are marked *

Please be aware that you comment is subject to our Privacy Policy.

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Prescribing Advice for GPs is powered by ClassicPress.
Connect to our RSS or Atom Feeds.