- Prescribing Advice for GPs - https://www.prescriber.org.uk -

Europe wide suspension for Rosiglitazone

The NHS Central Alerting System has issued an alert advising that the European Committee on Medicinal Products for Human Use has recommended the suspension of the marketing authorisations for rosiglitazone (Avandia®, Avandamet®) across the European Union.

The full content of the alert will be available tomorrow but registered users and those who receive CAS alerts by email will be able to access the content now. The European Medicines Agency will also

Clinicians are advised to put in place a system to ensure that all patients are reviewed and changed to another suitable treatment in line with NICE recommendations. This could be at the next routine appointment, or sooner if this will reduce patient anxiety.

Patients are advised to continue with their treatment but should contact the healthcare professional supervising their diabetic treatment.

Action: Clinicians should be aware of this product withdrawal. Patients being prescribed rosiglitazone should be identified and contacted to discuss any necessary changes to treatment.

Update: The European Medicines Agency (EMA) and the Medicines and Healthcare products Regulatory Agency (MHRA) websites both now contain infomation about the recommendation for the withdrawal.