Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

MTRAC Reviews - July 2014

MTRAC issued a new Commissioning Support guidance in July 2014. The review covers DPP-4 inhibitors.

This Commissioning Guidance (PDF) reviews the evidence for all of the currently available 'gliptins'. It notes that no significant differences in blood glucose reducing efficacy have were identified in a systematic review or in a direct comparison between sitagliptin and saxagliptin. It is also noted that the current NICE Guidance recommends continued treatment with DDP-4 inhibitors only when there is a beneficial metabolic response (HbA1c reduction of 0.5% or 5-6mmol/mol). This guidance summary recommends that, "if a gliptin is to be used, it is advised that the gliptin is selected based on the appropriate licensed indications, with the lowest acquisition cost".

Action: Clinicians should be aware of these reviews and use the recommendations to guide appropriate use of these medicines in current practice.

Share 'MTRAC Reviews - July 2014' on Email Share 'MTRAC Reviews - July 2014' on Delicious Share 'MTRAC Reviews - July 2014' on Digg Share 'MTRAC Reviews - July 2014' on Facebook Share 'MTRAC Reviews - July 2014' on Google+ Share 'MTRAC Reviews - July 2014' on reddit Share 'MTRAC Reviews - July 2014' on StumbleUpon Share 'MTRAC Reviews - July 2014' on Twitter

atomic-wealth

No Comments to “MTRAC Reviews - July 2014”

Leave a Comment

(required)

(required)


Prescribing Advice for GPs is powered by WordPress.
Subscribe for Free to our RSS or Atom Feeds for New Entries.
Akismet has protected Prescribing Advice for GPs from 789,209 spam comments.

atomic-wealth
fond-illness
summer