Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Drug Safety Update - September 2016

The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for September 2016 (PDF).

This issue contains updated advice on emergency hormonal contraception in patients taking hepatic enzyme inducers. It is now advised that women taking hepatic enzyme inducers, or who have taken them in the previous 4 weeks, are recommended to preferably use a non-hormonal emergency contraceptive - i.e. a copper intrauterine device. Where this is not possible a double dose of levonorgestrel must be used. It is also advised that a pregnancy test is performed to exclude pregnancy after use of levonorgestrel-containing emergency contraception and advice sought if they do become pregnant.

Hepatic enzyme inducers include medicines used to treat:

  • epilepsy (e.g. barbiturates, primidone, phenytoin, carbamazepine)
  • tuberculosis (e.g. rifampicin, rifabutin)
  • HIV (e.g. ritonavir, efavirenz)
  • fungal infections (e.g. griseofulvin)
  • and Herbal remedies that contain St John’s wort (Hypericum perforatum)

This issue also contains additional information that posaconazole suspension and tablets are not dose equivalent as noted in the summary of letters to healthcare professionals in last month's update.

Action: Clinicians should be aware of this month's new guidance and implement any necessary changes to practice.

Share 'Drug Safety Update - September 2016' on Email Share 'Drug Safety Update - September 2016' on Delicious Share 'Drug Safety Update - September 2016' on Digg Share 'Drug Safety Update - September 2016' on Facebook Share 'Drug Safety Update - September 2016' on Google+ Share 'Drug Safety Update - September 2016' on reddit Share 'Drug Safety Update - September 2016' on StumbleUpon Share 'Drug Safety Update - September 2016' on Twitter

atomic-wealth

No Comments to “Drug Safety Update - September 2016”

Leave a Comment

(required)

(required)


Prescribing Advice for GPs is powered by WordPress.
Subscribe for Free to our RSS or Atom Feeds for New Entries.
Akismet has protected Prescribing Advice for GPs from 788,922 spam comments.

atomic-wealth
fond-illness
summer