Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Fluphenazine decanoate discontinued

The manufacturer of fluphenazine decanoate (Modecate®) injection has written to healthcare professionals advising that this product will be discontinued by the end of 2018.

The letter details unpredictable supplies of the active ingredient from the single global manufacturer as the reason for this decision. It is noted that this decision is not due to any safety concerns. Both injection strengths (25mg/ml and 100mg/ml) are being discontinued with manufacturing ceasing in mid-2018 with supplies in the United Kingdom expected to run out by the end of 2018.

Action: Clinicians should be aware of this product being discontinued. It would be prudent to run clinical system searches to identify any patients who are currently prescribed this product to allow a review and arrangements made to identify a suitable alternative.

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9 Comments to “Fluphenazine decanoate discontinued”

  1. My brother has suffered from schizophrenia for years and his injections were just stopped with no warning, he is now in a hell of a state, I am very worried about him.

    Comment by E Lee — May 15, 2018 #

  2. Discontinuing effective mediation for some people is inhumane.

    Comment by Christine — April 15, 2018 #

    1. @Christine,

      There are alternatives available, some of which are generally considered to be better treatments. As the popularity of a medicine declines, who should be responsible for keeping it available when it becomes economically nonviable to produce for companies that need to make a profit?

      Comment by Matthew Robinson — April 16, 2018 #

  3. Very irresponsible for discontinuing this.

    Comment by L — April 11, 2018 #

  4. Absolutely agree with the above!
    Seems like the NHS & drug companies do not fear being old or mental! What goes round comes back round! Playing with lives, getting rid of old vulnerable people to cut costs is so evil. May God bring these people to sense.

    Comment by Justice — November 22, 2017 #

    1. @Justice

      While I can't speak for the drug companies having never worked for them, I can speak for the NHS and unfortunately this is beyond our control. We are usually just as frustrated as our patients when an effective drug is removed from the market when there are no safety concerns prompting the withdrawal. Sadly, pharmaceuticals are product of business, and when the business deems that it is no longer commercially viable to make a product there is nothing anyone can do to stop them. No one could stop a car maker from producing a model in it's line up.

      On a more positive note, it does seem that this medication remains, for the time being at least, widely available.

      Comment by Matthew Robinson — November 23, 2017 #

  5. My son has been given this medication in a form of injection every two weeks for Schizophrenia. I want to know what other medications that are safe to use beside this fluphenazine. This is outrageous how the pharmaceutical companies are getting richer and the government is allowing this to happen. Something needs to be done.

    Comment by Esther M Denis — November 10, 2017 #

  6. Why is this product discontinued?

    Comment by Kathy DeLuca — September 22, 2017 #

  7. God help people with Schizophrenia whom have been on Modecate most of their lives.
    My mother had been on it for over 60 years until a new consultant misdiagnosed her as having full blown dementia around 12 years ago. We since proved the misdiagnosis but they never put her back on the Modecate. The alternatives have not worked for her and her life has been hell ever since. So people beware, (I am not scare mongering here) you so need to be prepared for this. I still think there is so much more to this than the public are being told. I just can't help feeling we are being fed a load of nonsense. Schizophrenia not treated correctly can kill you. All of the alternative medications carry a risk of sudden death printed in the leaflets. In my opinion, this is about thinning the population down to unburden the grossly overloaded NHS, the mentally disabled being the most vulnerable and easiest of targets. I am disgusted to say the least.

    Comment by Alan Anderson — September 21, 2017 #

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