Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Fluphenazine decanoate discontinued

The manufacturer of fluphenazine decanoate (Modecate®) injection has written to healthcare professionals advising that this product will be discontinued by the end of 2018.

The letter details unpredictable supplies of the active ingredient from the single global manufacturer as the reason for this decision. It is noted that this decision is not due to any safety concerns. Both injection strengths (25mg/ml and 100mg/ml) are being discontinued with manufacturing ceasing in mid-2018 with supplies in the United Kingdom expected to run out by the end of 2018.

Action: Clinicians should be aware of this product being discontinued. It would be prudent to run clinical system searches to identify any patients who are currently prescribed this product to allow a review and arrangements made to identify a suitable alternative.

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89 Comments to “Fluphenazine decanoate discontinued”

  1. My sister was given fluphenazine decanonate injections for 3 month to treat mental illness but again the symptoms are all back. She has lost much of the weight that she gained during the time she was on medication. What treatment should we give her for the recurring mood swing and mental disorders?

    Comment by Aceng Teddy — July 1, 2020 #

    1. @Aceng Teddy,

      There are lots of options available and the decision on which is the best for your sisters should be made by her and her doctor.

      Comment by Matthew Robinson — July 2, 2020 #

  2. Is fluphenazine decanonate USP still available to be used at the moment?

    Comment by Aceng Teddy — July 1, 2020 #

  3. Please keep me upto date with new developments on alternatives to discontinued modecate depot.
    My son was well controlled on it for 15 years. So far not doing well on other medications.

    Comment by Mr M. Cho — May 30, 2020 #

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