Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

Zafirlukast discontinued

The manufacturer of zafirlukast (Accolate®) has discontinued this product with effect from the end of March 2018. No further supplies are being made and it is predicted that minimal supplies will be available within the supply chain.

Commercial reasons are cited for this decision and it is stressed that there were no safety concerns with this medicine. Zafirlukast is a leukotriene receptor antagonist and as such the closest available alternative is montelukast.

Action: Clinicians should be aware of this product being discontinued. It would be prudent to run clinical system searches to identify any patients who are currently prescribed this product to allow a review and arrangements made to identify a suitable alternative.

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21 Comments to “Zafirlukast discontinued”

  1. My GP, chemists and consultant were totally unaware until I researched it and found out it was discontinued. I'm totally disgusted that this can happen with no other alternative for us than to go back on a drug that previously caused bad side effects. I also had to go back on the montelukast and am still getting severe headaches although my asthma is a little better on it rather than on nothing like when I ran out of the zafirlukast. But definitely not as good as when on the zafirlukast, how is it allowed that they can just decide to suddenly discontinue a drug that keeps so many asthmatics stable at the drop of a hat because it doesn't make them enough money? It's unethical and dangerous.

    Comment by Kat — November 13, 2018 #
    Reply

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