Prescribing Advice for GPs

An NHS Prescribing Advisers' Blog

SMC Update - October 2019

The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines.

Glibenclamide (Amglidia®) has been rejected for use in the treatment of neonatal diabetes mellitus, for use in newborns, infants and children.

Triptorelin acetate (Decapeptyl®) has been accepted for us as adjuvant treatment in combination with tamoxifen or an aromatase inhibitor, of endocrine responsive early stage breast cancer in women at high risk of recurrence who are confirmed as premenopausal after completion of chemotherapy. For this indication, treatment initiation would normally be recommended by a specialist. This decision takes account of the benefits of a Patient Access Scheme (PAS) that improves the cost-effectiveness of triptorelin. This advice is contingent upon the continuing availability of the PAS in NHSScotland or a list price that is equivalent or lower.

Action: Clinicians should be aware of the recommendations of the SMC. Routine use of rejected and restricted medicines should be avoided.

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CKS Updates - September 2019

During September 2019 Clinical Knowledge Summaries were published or updated in the following areas.

The End of life care in children is new. The Hypercalcaemia topic has been significantly restructured in line with current evidence with new sections added covering prognosis and specialist assessment. The Leg ulcer - venous topic contains updated recommendations on managing an infected leg ulcer. The Retinal detachment topic has also been updated in line with current evidence and contains new sections on assessment and specialist management. The other topics have undergone reviews and minor restructures.

Action: Clinicians who see patients with any of these conditions may find the new and updated information useful when reviewing current clinical practice.

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