- Prescribing Advice for GPs - https://www.prescriber.org.uk -

SMC Update - December 2023

The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines.

Osilodrostat (Isturisa®) has been rejected for use in the treatment of endogenous Cushing’s syndrome in adults. The manufacturer failed to make a submission for this indication. In considering the product license, it would be expected that this medicine would be prescribed and monitored by a specialist.

Action: Clinicians should be aware of the recommendations of the SMC. Routine use of rejected and restricted medicines should be avoided.