Prescribing Advice for GPs https://www.prescriber.org.uk An NHS Prescribing Advisers' Blog Wed, 24 Feb 2021 09:19:35 +0000 en-GB hourly 1 https://wordpress.org/?v=5.6.2 /wp-content/uploads/fbrfg/favicon.ico Prescribing Advice for GPs https://www.prescriber.org.uk 32 32 NICE Guidance - February 2021 https://www.prescriber.org.uk/2021/02/nice-guidance-february-2021/ https://www.prescriber.org.uk/2021/02/nice-guidance-february-2021/#respond Wed, 24 Feb 2021 09:19:35 +0000 https://www.prescriber.org.uk/?p=1645 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of February 2021. This month is one technology appraisal that impacts upon primary care. The Dapagliflozin for treating chronic heart failure with reduced ejection fraction technology appraisal has been published. This treatment is recommended as an option […]

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Drug Safety Update - February 2021 https://www.prescriber.org.uk/2021/02/drug-safety-update-february-2021/ https://www.prescriber.org.uk/2021/02/drug-safety-update-february-2021/#respond Fri, 19 Feb 2021 08:42:23 +0000 https://www.prescriber.org.uk/?p=1644 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for February 2021 (PDF). This month readers are advised of further restrictions on the use of ulipristal acetate (Esmya®) for uterine fibroids due to the risk of serious liver injury. The temporary suspension has been lifted but it is recommended that this […]

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SMC Update - February 2021 https://www.prescriber.org.uk/2021/02/smc-update-february-2021/ https://www.prescriber.org.uk/2021/02/smc-update-february-2021/#respond Tue, 09 Feb 2021 08:39:59 +0000 https://www.prescriber.org.uk/?p=1643 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Formoterol / glycopyrronium / budesonide aerosol inhaler (Trixeo Aerosphere®) has been accepted for restricted use as a maintenance treatment in adult patients with moderate to severe chronic obstructive pulmonary disease (COPD) who are not adequately treated by a combination of an […]

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CKS Updates - January 2021 https://www.prescriber.org.uk/2021/02/cks-updates-january-2021/ https://www.prescriber.org.uk/2021/02/cks-updates-january-2021/#respond Tue, 02 Feb 2021 10:15:43 +0000 https://www.prescriber.org.uk/?p=1642 During January 2021 Clinical Knowledge Summaries were published or updated in the following areas. Anticoagulation - oral Diabetes - type 2 Jaundice in adults Jaundice in the newborn Mastitis and breast abscess Mental health in students Squint in children Tennis elbow The Mental health in students topic is new. All of the other topics have […]

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NICE Guidance - January 2021 https://www.prescriber.org.uk/2021/01/nice-guidance-january-2021/ https://www.prescriber.org.uk/2021/01/nice-guidance-january-2021/#respond Thu, 28 Jan 2021 09:03:24 +0000 https://www.prescriber.org.uk/?p=1641 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of January 2021. This month is one evidence summary that impacts upon primary care. The Antimicrobial prescribing: delafloxacin for acute bacterial skin and skin structure infections evidence summary has been published. The likely place in therapy for […]

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SMC Update - January 2021 https://www.prescriber.org.uk/2021/01/smc-update-january-2021/ https://www.prescriber.org.uk/2021/01/smc-update-january-2021/#respond Wed, 20 Jan 2021 08:26:00 +0000 https://www.prescriber.org.uk/?p=1640 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Melatonin prolonged-release (Slenyto®) has been rejected following a resubmission for use in the treatment of insomnia in children and adolescents aged 2 to 18 years with autism spectrum disorder and / or Smith-Magenis syndrome, where sleep hygiene measures have been insufficient. […]

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Drug Safety Update - January 2021 https://www.prescriber.org.uk/2021/01/drug-safety-update-january-2021/ https://www.prescriber.org.uk/2021/01/drug-safety-update-january-2021/#respond Fri, 08 Jan 2021 08:42:50 +0000 https://www.prescriber.org.uk/?p=1639 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for January 2021 (PDF). This month readers are advised of a review of the risks of major congenital malformations and of adverse neurodevelopmental outcomes for antiepileptic drugs conducted by the Commission on Human Medicines. It has confirmed that lamotrigine and levetiracetam are […]

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NICE Guidance - December 2020 https://www.prescriber.org.uk/2020/12/nice-guidance-december-2020/ https://www.prescriber.org.uk/2020/12/nice-guidance-december-2020/#respond Wed, 30 Dec 2020 09:07:00 +0000 https://www.prescriber.org.uk/?p=1638 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of December 2020. This month there are eight clinical guidelines, two COVID-19 Rapid Guidelines and one technology appraisal that impact upon primary care. The seven clinical guidelines of relevance to primary care this month have all been […]

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Drug Safety Update - December 2020 https://www.prescriber.org.uk/2020/12/drug-safety-update-december-2020/ https://www.prescriber.org.uk/2020/12/drug-safety-update-december-2020/#respond Mon, 21 Dec 2020 08:23:45 +0000 https://www.prescriber.org.uk/2020/12/drug-safety-update-december-2020/ The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for December 2020 (PDF). This month readers are advised that systemic and inhaled fluoroquinolones are associated with a small increased risk of heart valve regurgitation. Fluoroquinolones are only recommended for use in serious, life-threatening bacterial infections. It is recommended that other options […]

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SMC Update - December 2020 https://www.prescriber.org.uk/2020/12/smc-update-december-2020/ https://www.prescriber.org.uk/2020/12/smc-update-december-2020/#respond Tue, 08 Dec 2020 09:07:08 +0000 https://www.prescriber.org.uk/?p=1636 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Mexiletine (Namuscla®) has been accepted for restricted use in the symptomatic treatment of myotonia in adult patients with non-dystrophic myotonic disorders. It is noted that this advice applies only in the context of an approved NHSScotland Patient Access Scheme (PAS) arrangement […]

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CKS Updates - November 2020 https://www.prescriber.org.uk/2020/12/cks-updates-november-2020/ https://www.prescriber.org.uk/2020/12/cks-updates-november-2020/#respond Wed, 02 Dec 2020 08:34:30 +0000 https://www.prescriber.org.uk/?p=1635 During November 2020 Clinical Knowledge Summaries were updated in the following areas. Dupuytren's disease Giant cell arteritis Hyponatraemia Macular degeneration - age-related Menopause Osgood-Schlatter disease Support for adult carers All of the topics have been reviewed and updated in keeping with current NICE guidance with minor layout changes. The Menopause topic now includes a lower […]

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NICE Guidance - November 2020 https://www.prescriber.org.uk/2020/11/nice-guidance-november-2020/ https://www.prescriber.org.uk/2020/11/nice-guidance-november-2020/#respond Thu, 26 Nov 2020 10:46:58 +0000 https://www.prescriber.org.uk/?p=1634 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of November 2020. This month is one guideline and one medtech innovation briefing that impact upon primary care. The Human and animal bites: antimicrobial prescribing guideline has been published. It sets out an antimicrobial prescribing strategy for […]

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Drug Safety Update - November 2020 https://www.prescriber.org.uk/2020/11/drug-safety-update-november-2020/ https://www.prescriber.org.uk/2020/11/drug-safety-update-november-2020/#respond Wed, 18 Nov 2020 08:20:21 +0000 https://www.prescriber.org.uk/?p=1633 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for November 2020 (PDF). This month readers are advised that modafinil potentially increases the risk of congenital malformations when used in pregnancy. Modafinil should not be used during pregnancy and women of childbearing potential must use effective contraception during treatment and for […]

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SMC Update - November 2020 https://www.prescriber.org.uk/2020/11/smc-update-november-2020/ https://www.prescriber.org.uk/2020/11/smc-update-november-2020/#respond Wed, 11 Nov 2020 08:17:13 +0000 https://www.prescriber.org.uk/?p=1632 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Patiromer (Veltassa®) has been rejected for use in the treatment of hyperkalaemia in adults. The submitting company did not present a sufficiently robust economic analysis to gain acceptance by SMC. It should be noted the NICE Guidance exists for England and […]

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CKS Updates - October 2020 https://www.prescriber.org.uk/2020/11/cks-updates-october-2020/ https://www.prescriber.org.uk/2020/11/cks-updates-october-2020/#respond Wed, 04 Nov 2020 08:45:52 +0000 https://www.prescriber.org.uk/?p=1631 During October 2020 Clinical Knowledge Summaries were updated in the following areas. Acute childhood limp Bronchiectasis Gastroenteritis Hand foot and mouth disease Multiple sclerosis Neck lump All of the topics have been reviewed and updated in keeping with current NICE guidance with minor layout changes. The Gastroenteritis topic has undergone major restructuring, with several nodes […]

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NICE Guidance - October 2020 https://www.prescriber.org.uk/2020/10/nice-guidance-october-2020/ https://www.prescriber.org.uk/2020/10/nice-guidance-october-2020/#respond Wed, 28 Oct 2020 12:57:40 +0000 https://www.prescriber.org.uk/?p=1630 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of October 2020. This month there are three guidelines, one technology appraisal and one antimicrobial guideline that impact upon primary care. The COVID-19 rapid guideline: managing symptoms (including at the end of life) in the community guideline […]

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Drug Safety Update - October 2020 https://www.prescriber.org.uk/2020/10/drug-safety-update-october-2020/ https://www.prescriber.org.uk/2020/10/drug-safety-update-october-2020/#respond Fri, 23 Oct 2020 11:51:32 +0000 https://www.prescriber.org.uk/2020/10/drug-safety-update-october-2020/ The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for October 2020 (PDF). This month readers are advised of new guidance that has been published on monitoring of patients on warfarin and other anticoagulants during the COVID-19 pandemic. In particular it is noted that acute illness may exaggerate the effect of […]

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SMC Update - October 2020 https://www.prescriber.org.uk/2020/10/smc-update-october-2020/ https://www.prescriber.org.uk/2020/10/smc-update-october-2020/#respond Tue, 13 Oct 2020 08:48:31 +0000 https://www.prescriber.org.uk/?p=1628 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Budesonide orodispersible (Jorveza®) has been accepted for restricted use in the treatment of eosinophilic oesophagitis (EoE) in adults (older than 18 years of age). The restriction limits use to patients unsuccessfully treated with proton pump inhibitors. Action: Clinicians should be aware […]

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CKS Updates - September 2020 https://www.prescriber.org.uk/2020/10/cks-updates-september-2020/ https://www.prescriber.org.uk/2020/10/cks-updates-september-2020/#respond Mon, 05 Oct 2020 07:53:06 +0000 https://www.prescriber.org.uk/?p=1627 During September 2020 Clinical Knowledge Summaries were updated in the following areas. Bone and soft tissue sarcoma - recognition and referral Brain and central nervous system cancers - recognition and referral Breast cancer - recognition and referral Childhood cancers - recognition and referral Gastrointestinal tract (lower) cancers - recognition and referral Gastrointestinal tract (upper) cancers […]

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NICE Guidance - September 2020 https://www.prescriber.org.uk/2020/10/nice-guidance-september-2020/ https://www.prescriber.org.uk/2020/10/nice-guidance-september-2020/#respond Thu, 01 Oct 2020 08:27:19 +0000 https://www.prescriber.org.uk/?p=1626 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of September 2020. This month there are three guidelines, one technology appraisal and one antimicrobial guideline that impact upon primary care. The Low back pain and sciatica in over 16s: assessment and management guideline has been updated. […]

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Drug Safety Update - September 2020 https://www.prescriber.org.uk/2020/09/drug-safety-update-september-2020/ https://www.prescriber.org.uk/2020/09/drug-safety-update-september-2020/#respond Thu, 24 Sep 2020 07:07:26 +0000 https://www.prescriber.org.uk/?p=1625 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for September 2020 (PDF). This month readers are advised of new recommendations following a review of the risks of dependence and addiction associated with prolonged use of opioid medicines (opioids) for non-cancer pain. Before prescribing opioids it is advised that clinicians discuss […]

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SMC Update - September 2020 https://www.prescriber.org.uk/2020/09/smc-update-september-2020/ https://www.prescriber.org.uk/2020/09/smc-update-september-2020/#respond Wed, 09 Sep 2020 08:04:21 +0000 https://www.prescriber.org.uk/?p=1624 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Sodium zirconium cyclosilicate (Lokelma®) has been accepted for restricted use, following a resubmission, for use in the treatment of hyperkalaemia in adult patients. The restriction limits use to patients with hyperkalaemia (defined as a serum potassium of >6.0mmol/L) with chronic kidney […]

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CKS Updates - August 2020 https://www.prescriber.org.uk/2020/09/cks-updates-august-2020/ https://www.prescriber.org.uk/2020/09/cks-updates-august-2020/#respond Thu, 03 Sep 2020 08:01:48 +0000 https://www.prescriber.org.uk/?p=1623 During August 2020 Clinical Knowledge Summaries were published or updated in the following areas. Analgesia - mild-to-moderate pain Appendicitis Constipation in children HIV infection and AIDS Meningitis - bacterial meningitis and meningococcal disease Restless legs syndrome All of the topics have been reviewed and undergone minor restructuring. The Appendicitis topic has been significantly restructured in […]

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Drug Safety Update - August 2020 https://www.prescriber.org.uk/2020/08/drug-safety-update-august-2020/ https://www.prescriber.org.uk/2020/08/drug-safety-update-august-2020/#respond Thu, 27 Aug 2020 07:19:44 +0000 https://www.prescriber.org.uk/?p=1622 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for August 2020 (PDF). This month readers are advised that clozapine blood levels may need to be monitored more frequently in certain situations, for example if a patient starts or stops smoking, if taking concomitant medications that impact on blood levels or […]

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NICE Guidance - August 2020 https://www.prescriber.org.uk/2020/08/nice-guidance-august-2020/ https://www.prescriber.org.uk/2020/08/nice-guidance-august-2020/#respond Wed, 19 Aug 2020 08:49:27 +0000 https://www.prescriber.org.uk/?p=1621 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of August 2020. This month is one guideline and one COVID-19 rapid guideline that impact upon primary care. The Surgical site infections: prevention and treatment guideline has been updated. It covers preventing and treating surgical site infections […]

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