Prescribing Advice for GPs https://www.prescriber.org.uk An NHS Prescribing Advisers' Blog Sat, 17 Apr 2021 15:03:21 +0000 en-GB hourly 1 https://wordpress.org/?v=5.7.1 /wp-content/uploads/fbrfg/favicon.ico Prescribing Advice for GPs https://www.prescriber.org.uk 32 32 SMC Update - April 2021 https://www.prescriber.org.uk/2021/04/smc-update-april-2021/ https://www.prescriber.org.uk/2021/04/smc-update-april-2021/#respond Tue, 13 Apr 2021 07:06:45 +0000 https://www.prescriber.org.uk/?p=1653 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Dapagliflozin (Forxiga®) has been accepted for use in adults for the treatment of symptomatic chronic heart failure with reduced ejection fraction. Action: Clinicians should be aware of the recommendations of the SMC. Routine use of rejected and restricted medicines should be […]

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CKS Updates - March 2021 https://www.prescriber.org.uk/2021/04/cks-updates-march-2021/ https://www.prescriber.org.uk/2021/04/cks-updates-march-2021/#respond Tue, 06 Apr 2021 07:22:28 +0000 https://www.prescriber.org.uk/?p=1652 During March 2021 Clinical Knowledge Summaries were published or updated in the following areas. Bruising Chlamydia - uncomplicated genital Contraception - progestogen-only methods Earwax Gilbert's syndrome Immunizations - childhood Itch - widespread Obstructive sleep apnoea syndrome Platelets - abnormal counts and cancer The Platelets - abnormal counts and cancer topic is new. The other topics […]

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NICE Guidance - March 2021 https://www.prescriber.org.uk/2021/03/nice-guidance-march-2021/ https://www.prescriber.org.uk/2021/03/nice-guidance-march-2021/#respond Wed, 31 Mar 2021 08:18:04 +0000 https://www.prescriber.org.uk/?p=1651 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of March 2021. This month are four guidelines that impact upon primary care. The Secondary bacterial infection of eczema and other common skin conditions: antimicrobial prescribing guideline has been published. It sets out an antimicrobial prescribing strategy […]

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Drug Safety Update - March 2021 https://www.prescriber.org.uk/2021/03/drug-safety-update-march-2021/ https://www.prescriber.org.uk/2021/03/drug-safety-update-march-2021/#respond Thu, 25 Mar 2021 08:36:57 +0000 https://www.prescriber.org.uk/?p=1650 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for March 2021 (PDF). This month readers are advised of an increased risk of non-melanoma skin cancer and progressive multifocal encephalopathy (PML) in patients taking bendamustine (Levact®). Bendamustine is an anti-cancer medicine so it is expected that this advice applies to specialists […]

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No Smoking Day - 2021 https://www.prescriber.org.uk/2021/03/no-smoking-day-2021/ https://www.prescriber.org.uk/2021/03/no-smoking-day-2021/#respond Tue, 09 Mar 2021 08:54:15 +0000 https://www.prescriber.org.uk/?p=1649 Tomorrow is No Smoking Day. The theme and support materials for this year have been developed in collaboration between ASH and Breathe 2025. The theme this year is that "Quitting smoking doesn’t have to be stressful" with the evidence supporting improved health and well-being after stopping smoking. Key messages for this year are: Quitting smoking […]

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SMC Update - March 2021 https://www.prescriber.org.uk/2021/03/smc-update-march-2021/ https://www.prescriber.org.uk/2021/03/smc-update-march-2021/#respond Mon, 08 Mar 2021 14:58:00 +0000 https://www.prescriber.org.uk/?p=1648 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Beclometasone / formoterol / glycopyrronium (Trimbow®) has been accepted for use as a maintenance treatment of asthma, in adults not adequately controlled with a maintenance combination of a long-acting beta2-agonist and medium dose of inhaled corticosteroid, and who experienced one or […]

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Aminophylline and Morphine Granules to be discontinued https://www.prescriber.org.uk/2021/03/aminophylline-and-morphine-granules-to-be-discontinued/ https://www.prescriber.org.uk/2021/03/aminophylline-and-morphine-granules-to-be-discontinued/#respond Thu, 04 Mar 2021 07:57:34 +0000 https://www.prescriber.org.uk/?p=1647 The MHRA Central Alerting System has issued two alerts warning that aminophylline tablets and morphine sulphate prolonged release granules for oral suspension are both being discontinued. Aminophylline (Phyllocontin®) modified release tablets are being discontinued in both the 225mg and 350mg strengths. Remaining supplies in the distribution chain are expected to be exhausted by early April […]

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CKS Updates - February 2021 https://www.prescriber.org.uk/2021/03/cks-updates-february-2021/ https://www.prescriber.org.uk/2021/03/cks-updates-february-2021/#respond Mon, 01 Mar 2021 13:06:37 +0000 https://www.prescriber.org.uk/?p=1646 During February 2021 Clinical Knowledge Summaries were published or updated in the following areas. Addison's disease Contraception - IUS/IUD Contraception - emergency Immunizations - travel Insulin therapy in type 2 diabetes Multiple myeloma All of the topics have been reviewed and updated in keeping with current guidance with minor layout changes. The two Contraception topics […]

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NICE Guidance - February 2021 https://www.prescriber.org.uk/2021/02/nice-guidance-february-2021/ https://www.prescriber.org.uk/2021/02/nice-guidance-february-2021/#respond Wed, 24 Feb 2021 09:19:35 +0000 https://www.prescriber.org.uk/?p=1645 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of February 2021. This month is one technology appraisal that impacts upon primary care. The Dapagliflozin for treating chronic heart failure with reduced ejection fraction technology appraisal has been published. This treatment is recommended as an option […]

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Drug Safety Update - February 2021 https://www.prescriber.org.uk/2021/02/drug-safety-update-february-2021/ https://www.prescriber.org.uk/2021/02/drug-safety-update-february-2021/#respond Fri, 19 Feb 2021 08:42:23 +0000 https://www.prescriber.org.uk/?p=1644 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for February 2021 (PDF). This month readers are advised of further restrictions on the use of ulipristal acetate (Esmya®) for uterine fibroids due to the risk of serious liver injury. The temporary suspension has been lifted but it is recommended that this […]

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SMC Update - February 2021 https://www.prescriber.org.uk/2021/02/smc-update-february-2021/ https://www.prescriber.org.uk/2021/02/smc-update-february-2021/#respond Tue, 09 Feb 2021 08:39:59 +0000 https://www.prescriber.org.uk/?p=1643 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Formoterol / glycopyrronium / budesonide aerosol inhaler (Trixeo Aerosphere®) has been accepted for restricted use as a maintenance treatment in adult patients with moderate to severe chronic obstructive pulmonary disease (COPD) who are not adequately treated by a combination of an […]

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CKS Updates - January 2021 https://www.prescriber.org.uk/2021/02/cks-updates-january-2021/ https://www.prescriber.org.uk/2021/02/cks-updates-january-2021/#respond Tue, 02 Feb 2021 10:15:43 +0000 https://www.prescriber.org.uk/?p=1642 During January 2021 Clinical Knowledge Summaries were published or updated in the following areas. Anticoagulation - oral Diabetes - type 2 Jaundice in adults Jaundice in the newborn Mastitis and breast abscess Mental health in students Squint in children Tennis elbow The Mental health in students topic is new. All of the other topics have […]

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NICE Guidance - January 2021 https://www.prescriber.org.uk/2021/01/nice-guidance-january-2021/ https://www.prescriber.org.uk/2021/01/nice-guidance-january-2021/#respond Thu, 28 Jan 2021 09:03:24 +0000 https://www.prescriber.org.uk/?p=1641 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of January 2021. This month is one evidence summary that impacts upon primary care. The Antimicrobial prescribing: delafloxacin for acute bacterial skin and skin structure infections evidence summary has been published. The likely place in therapy for […]

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SMC Update - January 2021 https://www.prescriber.org.uk/2021/01/smc-update-january-2021/ https://www.prescriber.org.uk/2021/01/smc-update-january-2021/#respond Wed, 20 Jan 2021 08:26:00 +0000 https://www.prescriber.org.uk/?p=1640 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Melatonin prolonged-release (Slenyto®) has been rejected following a resubmission for use in the treatment of insomnia in children and adolescents aged 2 to 18 years with autism spectrum disorder and / or Smith-Magenis syndrome, where sleep hygiene measures have been insufficient. […]

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Drug Safety Update - January 2021 https://www.prescriber.org.uk/2021/01/drug-safety-update-january-2021/ https://www.prescriber.org.uk/2021/01/drug-safety-update-january-2021/#respond Fri, 08 Jan 2021 08:42:50 +0000 https://www.prescriber.org.uk/?p=1639 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for January 2021 (PDF). This month readers are advised of a review of the risks of major congenital malformations and of adverse neurodevelopmental outcomes for antiepileptic drugs conducted by the Commission on Human Medicines. It has confirmed that lamotrigine and levetiracetam are […]

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NICE Guidance - December 2020 https://www.prescriber.org.uk/2020/12/nice-guidance-december-2020/ https://www.prescriber.org.uk/2020/12/nice-guidance-december-2020/#respond Wed, 30 Dec 2020 09:07:00 +0000 https://www.prescriber.org.uk/?p=1638 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of December 2020. This month there are eight clinical guidelines, two COVID-19 Rapid Guidelines and one technology appraisal that impact upon primary care. The seven clinical guidelines of relevance to primary care this month have all been […]

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Drug Safety Update - December 2020 https://www.prescriber.org.uk/2020/12/drug-safety-update-december-2020/ https://www.prescriber.org.uk/2020/12/drug-safety-update-december-2020/#respond Mon, 21 Dec 2020 08:23:45 +0000 https://www.prescriber.org.uk/2020/12/drug-safety-update-december-2020/ The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for December 2020 (PDF). This month readers are advised that systemic and inhaled fluoroquinolones are associated with a small increased risk of heart valve regurgitation. Fluoroquinolones are only recommended for use in serious, life-threatening bacterial infections. It is recommended that other options […]

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SMC Update - December 2020 https://www.prescriber.org.uk/2020/12/smc-update-december-2020/ https://www.prescriber.org.uk/2020/12/smc-update-december-2020/#respond Tue, 08 Dec 2020 09:07:08 +0000 https://www.prescriber.org.uk/?p=1636 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Mexiletine (Namuscla®) has been accepted for restricted use in the symptomatic treatment of myotonia in adult patients with non-dystrophic myotonic disorders. It is noted that this advice applies only in the context of an approved NHSScotland Patient Access Scheme (PAS) arrangement […]

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CKS Updates - November 2020 https://www.prescriber.org.uk/2020/12/cks-updates-november-2020/ https://www.prescriber.org.uk/2020/12/cks-updates-november-2020/#respond Wed, 02 Dec 2020 08:34:30 +0000 https://www.prescriber.org.uk/?p=1635 During November 2020 Clinical Knowledge Summaries were updated in the following areas. Dupuytren's disease Giant cell arteritis Hyponatraemia Macular degeneration - age-related Menopause Osgood-Schlatter disease Support for adult carers All of the topics have been reviewed and updated in keeping with current NICE guidance with minor layout changes. The Menopause topic now includes a lower […]

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NICE Guidance - November 2020 https://www.prescriber.org.uk/2020/11/nice-guidance-november-2020/ https://www.prescriber.org.uk/2020/11/nice-guidance-november-2020/#respond Thu, 26 Nov 2020 10:46:58 +0000 https://www.prescriber.org.uk/?p=1634 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of November 2020. This month is one guideline and one medtech innovation briefing that impact upon primary care. The Human and animal bites: antimicrobial prescribing guideline has been published. It sets out an antimicrobial prescribing strategy for […]

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Drug Safety Update - November 2020 https://www.prescriber.org.uk/2020/11/drug-safety-update-november-2020/ https://www.prescriber.org.uk/2020/11/drug-safety-update-november-2020/#respond Wed, 18 Nov 2020 08:20:21 +0000 https://www.prescriber.org.uk/?p=1633 The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for November 2020 (PDF). This month readers are advised that modafinil potentially increases the risk of congenital malformations when used in pregnancy. Modafinil should not be used during pregnancy and women of childbearing potential must use effective contraception during treatment and for […]

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SMC Update - November 2020 https://www.prescriber.org.uk/2020/11/smc-update-november-2020/ https://www.prescriber.org.uk/2020/11/smc-update-november-2020/#respond Wed, 11 Nov 2020 08:17:13 +0000 https://www.prescriber.org.uk/?p=1632 The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Patiromer (Veltassa®) has been rejected for use in the treatment of hyperkalaemia in adults. The submitting company did not present a sufficiently robust economic analysis to gain acceptance by SMC. It should be noted the NICE Guidance exists for England and […]

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CKS Updates - October 2020 https://www.prescriber.org.uk/2020/11/cks-updates-october-2020/ https://www.prescriber.org.uk/2020/11/cks-updates-october-2020/#respond Wed, 04 Nov 2020 08:45:52 +0000 https://www.prescriber.org.uk/?p=1631 During October 2020 Clinical Knowledge Summaries were updated in the following areas. Acute childhood limp Bronchiectasis Gastroenteritis Hand foot and mouth disease Multiple sclerosis Neck lump All of the topics have been reviewed and updated in keeping with current NICE guidance with minor layout changes. The Gastroenteritis topic has undergone major restructuring, with several nodes […]

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NICE Guidance - October 2020 https://www.prescriber.org.uk/2020/10/nice-guidance-october-2020/ https://www.prescriber.org.uk/2020/10/nice-guidance-october-2020/#respond Wed, 28 Oct 2020 12:57:40 +0000 https://www.prescriber.org.uk/?p=1630 The National Institute for Health and Care Excellence (NICE) have published new or updated guidance for the month of October 2020. This month there are three guidelines, one technology appraisal and one antimicrobial guideline that impact upon primary care. The COVID-19 rapid guideline: managing symptoms (including at the end of life) in the community guideline […]

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Drug Safety Update - October 2020 https://www.prescriber.org.uk/2020/10/drug-safety-update-october-2020/ https://www.prescriber.org.uk/2020/10/drug-safety-update-october-2020/#respond Fri, 23 Oct 2020 11:51:32 +0000 https://www.prescriber.org.uk/2020/10/drug-safety-update-october-2020/ The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for October 2020 (PDF). This month readers are advised of new guidance that has been published on monitoring of patients on warfarin and other anticoagulants during the COVID-19 pandemic. In particular it is noted that acute illness may exaggerate the effect of […]

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